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    Virus

    Anonymous
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    Post by Guest Thu Dec 09, 2021 3:26 pm

    mislim da se polako pojavljuju podaci koji ukazuju na drugačiju situaciju sa omikronom

    omikron sada ima jedan gen koji je verovatno potekao od starog korona virusa, a on izaziva običnu prehladu, pretpostavka je da su se u ćeliji našli dva različita virusa i razmenili genetski materijal, zato su simptomi izmenjeni

    drugo, analize otpadnih voda u usa pokazuju daleko veći broj zaraženih nego što je registrovano, što bi moglo da znači da simptomi koje ljudi imaju nisu dovoljno ozbiljni da ih nateraju da odu kod lekara ili na testiranje

    to bi moglo da promeni sliku o ukupnom % težih slučajeva, a analiza otpadnih voda je verovatno najpouzdanija kao pokazatelj prisustva infekcije, uvek je postojao određeni udeo asimptomatskih i netestiranih ljudi, ali nikada nije postojao veliki broj ljudi koji ne pišaju
    rumbeando

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    Post by rumbeando Thu Dec 09, 2021 3:41 pm

    Talason wrote:drugo, analize otpadnih voda u usa pokazuju daleko veći broj zaraženih nego što je registrovano, što bi moglo da znači da simptomi koje ljudi imaju nisu dovoljno ozbiljni da ih nateraju da odu kod lekara ili na testiranje

    Hvala na toj informaciji.

    To jeste jedno moguće tumačenje i nadajmo se da je tačno, drugo je da su količine virusa po jednoj osobi daleko veće u odnosu na ranije talase. Naravno, moguća je i kombinacija ta dva.


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    rumbeando

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    Post by rumbeando Thu Dec 09, 2021 4:20 pm

    rumbeando

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    Post by rumbeando Thu Dec 09, 2021 4:25 pm

    Nova detaljna in vitro studija na živom virusu i antitelima iz krvi vakcinisanih dvema dozama (nema podataka o zaštiti busterovanih) i preležalih, tj. o sprečavanju zaražavanja omikronom (krajnje desna stavka na graficima): od vakcinisanih dvema dozama najbolje su zaštićeni oni koji su prvo primili AstraZeneku, a zatim Fajzer (13 od 20 uzoraka krvi uspelo je da neutrališe omikron), kod duplog Fajzera 9 od 20 uzoraka, kod duple Moderne svega jedan od 20 (a i on na pragu, tj. isprekidanoj liniji), a kod duple AstraZeneke nijedan.

    Od preležalih nevakcinisanih, krv onih koji su preležali alfu ne neutrališe omikron, betu 1 od 8, a deltu 1 od 7.

    Od vakcinisanih pa preležalih i obrnuto krv u velikom procentu slučajeva neutrališe omikron.

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    Spikevax = Moderna
    ChadOx1 = Astrazeneca
    BNT162b2 = Biontech/Pfizer
    B.1.1.7 = alfa
    B.1.351 = beta
    B.1.617.2 = delta
    B.1.1.529 = omikron
    convalescent = preležali alfu, betu ili deltu

    Još jednom, sve ove studije ne govore ništa o zaštiti od teške bolesti i smrti pošto tu ne igraju ključnu ulogu antitela, već T i B ćelije.



    rumbeando

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    Post by rumbeando Thu Dec 09, 2021 5:05 pm

    5. dan uzastopno broj na respiratoru raste. Slučajevi i udeo pozitivnih i dalje opadaju.



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    https://www.b92.net/info/koronavirus/statistika.php
    rumbeando

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    Post by rumbeando Thu Dec 09, 2021 6:09 pm

    ​Od klastera sa zasad 19 zaraženih omikronom (još nije potvrđen kod svih) u Kleveu, nemačkom gradiću od oko 50.000 stanovnika uz holandsku granicu, koji su započela dva para i još jedna osoba, koji su bili u Južnoj Africi i u međusobnom kontaktu, jedna odrasla vakcinisana osoba i dvoje dece teško bolesni.
     
    Omicron confirmed in the Kleve district
    Covid after trip to South Africa - two children seriously ill

    The district of Kleve has the first clear evidence of the Omikron variant. The complete sequence analysis of a laboratory has now confirmed the suspicion for two index cases. These are a South African traveler and a contact person. Over the weekend, a laboratory had already substantiated the suspicion of the Omikron mutation for two other persons who were in South Africa, but had not yet definitively confirmed it.
    The Kleve district has now identified 19 index cases linked to this outbreak. Among the contacts are children who have not yet been vaccinated. The adults are all fully immunized. Two children are severely ill. One adult has a severe course of illness. All other persons who have tested positive have so far had a comparatively mild course of the disease. Some are asymptomatic.
    17 people tested positive come from Rees, one from Bedburg-Hau and one from Kevelaer. Among them are four South Africa travelers who had traveled in pairs but had contact with each other during the trip. For one of these persons, the omicron mutation has now been clearly confirmed. For two of them, the first laboratory results have at least confirmed the omicron suspicion. The laboratory result for the fourth person is currently still pending.  In addition, there is another person who was in South Africa and had contact with the two couples there. In addition, the Kleve district was able to determine seven initial contacts of the travelers. From this group comes the second person, for whom now the clear confirmation of the Omikron mutation is available. Finally, there are seven further contacts for whom a PCR test has meanwhile detected a corona infection.
    The health department is commissioning further laboratory sequencing in the coming weeks for samples from index cases associated with the travelers returning from Rees. This will be done in all cases where it can be done without re-smear. Laboratories often do not keep samples. This means that cases that have already been confirmed would have to be swabbed again for sequencing. However, since the first swabs were taken days ago, the viral load might not be sufficient.
    The investigation of additional contacts is ongoing. The health department is following the Robert Koch Institute's quarantine recommendations for suspected Omikron cases: Index cases and contacts are quarantined for 14 days in all cases. There is no way to shorten this time - even if there is complete immunization and freedom from symptoms.
    https://rp-online.de/nrw/staedte/kleve/omikron-im-kreis-kleve-bestaetigt-covid-nach-suedafrika-reise_aid-64520525 (prevod: Deepl)
    boomer crook

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    Post by boomer crook Thu Dec 09, 2021 7:05 pm

    jebote raspust ne moze da dodje dovoljno brzo


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    Post by MNE Thu Dec 09, 2021 9:49 pm

    https://www.sfchronicle.com/health/article/Omicron-outbreak-from-out-of-state-wedding-tied-16685845.php

    Eleven of the 12 confirmed COVID-19 cases tied to an omicron outbreak in the East Bay last week are among fully vaccinated and boosted staff members at Kaiser Permanente’s Oakland Medical Center, according to a spokesperson for the hospital.
    rumbeando

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    Post by rumbeando Thu Dec 09, 2021 10:39 pm







    rumbeando

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    Post by rumbeando Thu Dec 09, 2021 10:44 pm






    Edit: okačio čovek u međuvremenu i krive za broj umrlih u poređenju s ranijim talasima

    rumbeando

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    Post by rumbeando Thu Dec 09, 2021 11:46 pm

    A group of seven Germans aged 25 to 39 have contracted the Omikron variant of the coronavirus in South Africa, although all have already received their booster vaccination. Wolfgang Preiser, a member of the research consortium that discovered the variant, told the Tagesspiegel newspaper. (...)
    The individuals received these vaccines in this order:
    Persons 1 to 5: Biontech, Biontech, Biontech.
    Person 6: Biontech, Biontech, Moderna
    Person 7: Astrazeneca, Biontech, Biontech

    Booster vaccinations were administered to subjects between five and ten months after the second vaccinations. The booster vaccinations were at least one month but no more than two months ago. (...)
    None of the seven Germans had to deal with a severe course of the infection. "Of course, one can now say: these are young people anyway. But you can already assume that at least a severe course is prevented," Preiser said.
    https://www.tagesspiegel.de/wissen/erste-berichtete-booster-durchbrueche-mit-omikron-sieben-junge-deutsche-infizieren-sich-in-suedafrika-trotz-dritt-impfung/27879838.html (prevod: Deepl)
    rumbeando

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    Post by rumbeando Thu Dec 09, 2021 11:49 pm

    rumbeando

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    Post by rumbeando Thu Dec 09, 2021 11:57 pm

    ​ 
    Cases of the Omicron variant could be spreading even faster in England than in South Africa, according to a senior scientific adviser, who warned that the variant was a “very severe setback” to hopes of bringing the pandemic under control.
    Prof John Edmunds, an epidemiologist at the London School of Hygiene and Tropical Medicine and a member of the government’s Scientific Advisory Group for Emergencies (Sage), said that plan B measures announced by the prime minister [Boris Johnson] were “absolutely not an overreaction” even if Omicron turned out to be milder than the current dominant variant. (...)
    Speaking at the online event, Edmunds dismissed suggestions that the Omicron variant might be “good news” if it hospitalised people at only half the rate as the Delta variant. The hope comes largely from hospital admissions in South Africa, where the population is far younger than in the UK and so less likely to experience severe Covid illness in the first place. While the average age in the UK is just over 40, it is less than 28 in South Africa.
    Edmunds said there was “not a shred of evidence” that Omicron was half as pathogenic as the Delta variant, but added that even if this were the case, it might not make the difference people hoped for. “This is a very severe setback. There is no question about that.”
    “If you are worried about the time [at] which the NHS might start to get very stressed, then halving the hospitalisation rate means that buys you two to three days. I think it’s really silly to suggest this is good news; it couldn’t be further from that,” he added. “This is as bad news as you can possibly get, quite frankly.”
    It will take several weeks for scientists to get a sense of how severe the disease is in the UK, where the vast majority of people have some immunity against earlier variants either through vaccination or previous infection. This week, Pfizer released data from a small lab study suggesting that three shots of its vaccine might hold up well against the Omicron variant, but Edmunds said it was the most optimistic of five or so studies he had seen on vaccine protection against the variant.
    Despite the uncertainties, Edmunds said it was “absolutely critical” for people to get their booster doses “as rapidly as possible”: “I think it will help, and it will help very significantly, but I still think we are likely to be under quite a lot of pressure in a very short time.”
    https://www.theguardian.com/world/2021/dec/09/daily-omicron-cases-in-uk-could-exceed-60000-by-christmas-sage-adviser-says
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    Post by MNE Fri Dec 10, 2021 7:39 am

    rumbeando wrote:
    A group of seven Germans aged 25 to 39 have contracted the Omikron variant of the coronavirus in South Africa, although all have already received their booster vaccination. Wolfgang Preiser, a member of the research consortium that discovered the variant, told the Tagesspiegel newspaper. (...)
    The individuals received these vaccines in this order:
    Persons 1 to 5: Biontech, Biontech, Biontech.
    Person 6: Biontech, Biontech, Moderna
    Person 7: Astrazeneca, Biontech, Biontech

    Booster vaccinations were administered to subjects between five and ten months after the second vaccinations. The booster vaccinations were at least one month but no more than two months ago. (...)
    None of the seven Germans had to deal with a severe course of the infection. "Of course, one can now say: these are young people anyway. But you can already assume that at least a severe course is prevented," Preiser said.
    https://www.tagesspiegel.de/wissen/erste-berichtete-booster-durchbrueche-mit-omikron-sieben-junge-deutsche-infizieren-sich-in-suedafrika-trotz-dritt-impfung/27879838.html (prevod: Deepl)
    istraživač koji utvrdi nešto na osnovu sedam osoba nije istraživač, tako ja mogu na osnovu sebe i još šestorice koju znam da utvrdim da korona nije opasna jer je nama pala kao obična prehlada
    Anonymous
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    Post by Guest Fri Dec 10, 2021 8:38 am

    Ovo nije istraživanje.
    fikret selimbašić

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    Post by fikret selimbašić Fri Dec 10, 2021 9:56 am

    Za pola godine u BiH je umrlo 39,69 odsto više ljudi nego u istom periodu 2020. godine, objavila je Agencija za statistiku BiH.U prvih šest mjeseci ove godine umrle su 25.243 osobe, što u odnosu na isti period 2020. pokazuje rast za 39,69 posto (prošle godine umrla je 18.071 osoba) navodi se u izvještaju agencije.Naša zemlju se, takođe, od samog početka objavljivanja podataka vezanih za smrtnost od korone, nalazi u samom vrhu- prva u Evropi i druga u svijetu, kažu najnoviji podaci.


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    Zli stolar.
    Del Cap

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    Post by Del Cap Fri Dec 10, 2021 10:00 am

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    Post by MNE Fri Dec 10, 2021 10:04 am

    Cousin Billy wrote:Ovo nije istraživanje.
    šta god, ovo ne može da pretpostavi na osnovu 7 uzoraka

    But you can already assume that at least a severe course is prevented
    Anonymous
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    Post by Guest Fri Dec 10, 2021 10:06 am

    Kod ovih sedam ljudi
    Nektivni Ugnelj

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    Post by Nektivni Ugnelj Fri Dec 10, 2021 10:18 am

    Zabrinjavajuce je probijanje bustera svejedno.
    kondo

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    Post by kondo Fri Dec 10, 2021 12:39 pm

    probijan je buster i u srbiji onoliko


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    Nektivni Ugnelj

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    Post by Nektivni Ugnelj Fri Dec 10, 2021 12:46 pm

    Ali ne masovno tj rutinski kada je delta u pitanju. Pogotovu ne ove kombinacije vakcina
    rumbeando

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    Post by rumbeando Fri Dec 10, 2021 2:14 pm

    MNE wrote:šta god, ovo ne može da pretpostavi na osnovu 7 uzoraka

    Nisu u pitanju uzorci, već klaster koji čini tih 7 osoba.

    I piše da je verovatno izbegnut jedan težak tok bolesti (pretpostavljam da je taj izvukao neki prosek, mada s obzirom na starost ljudi, lako moguće da preteruje), Deepl je zabrljao s prevodom.

    Inače, rad tj. studija slučaja je poslata na recenziju:
    https://deliverypdf.ssrn.com/delivery.php?ID=684088071004065001097111097087001109026012051033042091108125103074073025068072102121101122062000122051045126009109016079073069005049095084082028087124116016124110019019005046078005006001011118127065089108114086126029121084080069113082121077120083126065&EXT=pdf&INDEX=TRUE
    rumbeando

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    Post by rumbeando Fri Dec 10, 2021 5:34 pm

    U zvaničnom dokumentu škotske vlade potvrđeno da broje sitno do dominacije omikrona.



    Nije da nema smisla, sa 1,3 na jučerašnjih 13,3% skočio je za nedelju dana.

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    rumbeando

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    Post by rumbeando Fri Dec 10, 2021 7:09 pm

    Spoiler:
    https://threadreaderapp.com/thread/1469350830864322560.html

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