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    VAKCINA

    kondo

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    Post by kondo Tue Apr 06, 2021 7:32 pm

    boomer crook wrote:
    Marius Lăcătuș wrote:

    ajde ne preteruj, nisu tvoji slušali pixies

    ja sam slusao pixies i jos upoznao nekog amera iz bostona i sokirao se sto on ne zna ko je frank black jel sam mislio, autosovinista kakav jesam, da tamo svi znaju za njih i samo to pice.

    ti jesi ali metalci sa karaburme slabo ili aj onako granično, glasne gitare i dobre melodije pa kao može kad se napijemo ali ne pišu fanovi pixies panagirike mejdenima ovde


    _____
    #FreeFacu

    Дакле, волео бих да се ЈСД Партизан угаси, али не и да сви (или било који) гробар умре.
    Sotir

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    Post by Sotir Tue Apr 06, 2021 7:33 pm

    San Saba Songbird wrote:mislim ZAISTA ti ne treba nikakav napor da slušaš Pixies.
    Тешкое.

    Кад је другар заменио Босанову за Експлојтед - Масакр лакнуло нам је.
    ćaća

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    Post by ćaća Tue Apr 06, 2021 7:49 pm

    bemty wrote:
    ćaća wrote:
     
    Association da, causality ne mogu još da utvrde, nemaju dovoljno podataka. Svejedno incidencija nije visoka. Proplematično je to što je MHRA prijavila sličan broj reakcija na 20 miliona vakcinisanih kao i Nemci na 2 miliona. To znači ili da Britanci kriju podatke ili ih neadekvatno prikupljaju.

    Uzgred, po standardnoj Yellow Card metodologiji prikupljanja podataka o ADR, uhvati se možda 10% slučajeva.

    u britaniji je AZ mnogo vise rasporedjena po demografskim kategorijama. u nemackoj je nisu jedno vreme davali starijima od 65, a medju mladjima su imali prioritetne grupe u koje su upadali i zaposleni u skolama (mahom zene) i jos jedna profesija koje ne mogu sad da se setim... uglavnom, ako je veci deo problema prisutan kod mladjih zena, a u Nemackoj su uglavnom pelcovali mladje zene ovom vakcinom, moguce je da je problem tamo bio vidljiviji. takodje je moguce, posto se radi o izuzetno retkom dogadjaju, da se radi i o genetskim predispozicijama koje su u nekim regijama prisutnije. nhs prikuplja podatke vrlo priljezno i jako bi me cudilo da se nesto krije na nivou drzave. prosto mislim da ne bi moglo da prodje, da ne bi imao ko da spreci objavljivanje u medicinskim casopisima.

    Obe pretpostavke su validne, u ovom trenutku nemamo dovoljno podataka zap zaključak.

    Osim ukoliko nešto nije promenjeno u poslednje vreme, informacije o neželjenim efektima ne prikuplja NHS već MHRA (delimično nezavisna institucija ali pod DoH). Problem je taj što prikupljanje informacija nije obavezno već je na dobrovoljnoj osnovi, to jest na savesti GPs. Možda je zbog pandemije u ovom slučaju napravljen izuzetak, ali ja to nisam nigde video.
    rumbeando

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    Post by rumbeando Tue Apr 06, 2021 9:58 pm

    Izašla je studija za efikasnost Sinofarmove i Sinovakove vakcine protiv britanskog i južnoafričkog soja.

    https://www.nejm.org/doi/full/10.1056/NEJMc2103022?query=featured_home

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    Sinofarm radi sa sličnom efikasnošću kao protiv originalnog virusa protiv britanske, a uglavnom ne radi protiv južnoafričke varijante.
     
    BBIBP = Sinopharm (pekinška verzija, koja se koristi kod nas)

    CoronaVac = SinoVac
     
    B.1.1.7 = United Kingdom 
    B.1.351 = South Africa 


    We first determined the serum neutralizing-antibody titer against wild-type pseudovirus...
    Notably, undetectable neutralization titers were seen in 4 of 34 convalescent serum samples, in 6 of 25 BBIBP-CorV serum samples, and in 4 of 25 CoronaVac serum samples.

    Dakle, 24% uzoraka seruma osoba vakcinisanih Sinofarmovom vakcinom nije delovalo protiv pseudovirusa s ključnim karakteristikama prvobitne verzije virusa.


    We next assessed the neutralizing activity of convalescent serum and vaccinee serum against D614G, B.1.1.7, and B.1.351 variants as compared with wild-type pseudovirus...
    For the BBIBP-CorV vaccinee serum samples, although the GMTs of neutralization against the variants were not significantly different from the GMTs against the wild-type virus, 20* serum samples showed complete or partial loss of neutralization against B.1.351...
    B.1.1.7 showed little resistance to the neutralizing activity of convalescent or vaccinee serum, whereas B.1.351 showed more resistance to the neutralization of both convalescent serum (by a factor of 2) and vaccinee serum (by a factor of 2.5 to 3.3) than the wild-type virus. Most of the vaccinee serum samples that were tested lost neutralizing activity

    20 od 25 uzoraka seruma osoba vakcinisanih Sinofarmovom vakcinom potpuno ili delimično je izgubilo sposobnost neutralizacije kada je u pitanju južnoafrička varijanta.
     
    Treba naglasiti da su uzorci seruma za Sinofarmovu vakcinu uzeti 2-3 nedelje posle vakcinacije drugom dozom tako da je moguće da bi rezultati bili nešto bolji da su uzeti kasnije.
    Sotir

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    Post by Sotir Tue Apr 06, 2021 10:11 pm

    Ма ово су резултати анализе крвног серума (плазме). Ниједна вакцина, па ни Фајзер, не даје такав ефекат на плазму.
    Чекај да ископам радове да поставим.
    Sotir

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    Post by Sotir Tue Apr 06, 2021 10:15 pm

    https://www.medrxiv.org/content/10.1101/2021.02.14.21251704v2.full

    Овде је анализа крвног серума према различитим сојевима
    Sotir

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    Post by Sotir Tue Apr 06, 2021 10:17 pm

    А овде је новији рад из Израела, наводе да је ефикасност Фајзера само незнатно слабија према новим сојевима
    https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(21)00136-0
    rumbeando

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    Post by rumbeando Tue Apr 06, 2021 10:23 pm

    Pa neće biti, ogromna većina (77%) uzoraka plazme vakcinisanih Fajzerom lepo je neutralisala južnoafrički soj 3 nedelje posle druge doze.

    VAKCINA - Page 14 454usCh
    https://www.nature.com/articles/s41591-021-01318-5
    Sotir

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    Post by Sotir Tue Apr 06, 2021 10:35 pm

    Румбе,
    Поента је да ефикасност крвне плазме после вакцинације није исто што и ефикасност вакцине. Вакцина је делотворнија.
    avatar
    Korisnik
    Korisnik

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    Post by ontheotherhand Tue Apr 06, 2021 11:41 pm

    VAKCINA - Page 14 20210406_173138
    Daï Djakman Faré

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    Post by Daï Djakman Faré Tue Apr 06, 2021 11:47 pm

    VAKCINA - Page 14 3579118792


    _____
    i would like to talk here about The Last of Us on HBO... and yeah, yeah i know.. the world is burning but lets just all sit and talk about television. again - what else are we doing with ourselves ? we are not creating any militias. but my god we still have the content. appraising content is the american modus vivendi.. that's why we are here for. to absorb the content and then render some sort of a judgment on content. because there is a buried hope that if enough people have the right opinion about the content - the content will get better which will then flow to our structures and make the world a better place
    rumbeando

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    Post by rumbeando Wed Apr 07, 2021 12:06 am

    The Washington State Department of Health (DOH) is investigating reports of people in the state who tested positive for COVID-19 more than two weeks after being fully vaccinated. Scientists call these “vaccine breakthrough” cases, which are expected with any vaccine.
    Large-scale clinical studies found that COVID-19 vaccines reduced the risk of getting COVID-19 in vaccinated people by up to 95% compared to people that did not receive the vaccine. However, the vaccines are not 100% effective in preventing infection. This means a small percentage of fully vaccinated people can be expected to still get COVID-19. These are identified as breakthrough cases.
    Out of one million fully vaccinated individuals in Washington state, epidemiologists report evidence of 102 breakthrough cases since February 1, 2021, which represents .01 percent of vaccinated people in Washington. Breakthrough cases have been identified in 18 counties. The majority of those in Washington state with confirmed vaccine breakthrough experienced only mild symptoms, if any. However, since February 1, eight people with vaccine breakthrough have been hospitalized. DOH is investigating two potential vaccine breakthrough cases where the patients died. Both patients were more than 80 years old and suffered underlying health issues.


    https://www.doh.wa.gov/Newsroom/Articles/ID/2720/Cases-of-COVID-19-vaccine-breakthrough-confirmed-in-Washington-state
    Anonymous
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    Post by Guest Wed Apr 07, 2021 10:18 am

    Nova istraživanja pokazuju da zaštita od kovida uz pomoć Modernine vakcine traje najmanje šest meseci, preneo je AP.



    U današnjem izveštaju Nju Ingland Džornal of Medisin navodi ono što je Fajzer naveo prošle nedelje o svojoj vakcini, a to je da i Modernina vakcina radi po istom principu.


    Oba izveštaja, kompanija Fajzer i Moderna, baziraju se na testovima na više desetina ljudi koji su primili vakcinu tokom studija koje su prethodile masovnoj imunizaciji.


    Međutim, te studije su urađene pre pojave novih, zaraznijih sojeva, zbog čega odvojeni izveštaj u medicinskom žurnalu piše o zabrinutosti zbog mutiranih tipova kovida.


    Fajzer i Moderna su saopštili da rade na ažuriranju njihovih vakcina ili mogućnosti davanja još jedne doze, ukoliko bude potrebna protiv novih sojeva.


    (b92)


    Ovo je baš kratko vreme delovanja. Pritom, moj nereprezentativni uzorak od četvoro prekookeanaca kaže da Moderna ima jake nuspojave, slične onima koje opisuju ljudi koji su primili AZ.


    Samo... jak im uzorak.
    Nektivni Ugnelj

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    Post by Nektivni Ugnelj Wed Apr 07, 2021 10:22 am

    Ma cime god da ste se vakcinisali planirajte sledece za 6 meseci. Ja tako.
    plavaivy

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    Post by plavaivy Wed Apr 07, 2021 10:27 am

    evo dobila revaks fajzera..solidna guzva,pomalo haoticno ali ok ceka se oko sat vremena ali unutra sto je super ..ispricala se sa nekim preslatkim i prepametnim detetom (20god) VAKCINA - Page 14 1399639816 studentom..kaze poslednjih 7dana od zavrsetka ispitnog roka studentske zurke od 200,300 ljudi ne prestaju..on mica ne ide zbog odgovornosti ,secer VAKCINA - Page 14 3826186726
    lalinea

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    Post by lalinea Wed Apr 07, 2021 10:45 am

    Hans wrote:Nova istraživanja pokazuju da zaštita od kovida uz pomoć Modernine vakcine traje najmanje šest meseci, preneo je AP.



    U današnjem izveštaju Nju Ingland Džornal of Medisin navodi ono što je Fajzer naveo prošle nedelje o svojoj vakcini, a to je da i Modernina vakcina radi po istom principu.


    Oba izveštaja, kompanija Fajzer i Moderna, baziraju se na testovima na više desetina ljudi koji su primili vakcinu tokom studija koje su prethodile masovnoj imunizaciji.


    Međutim, te studije su urađene pre pojave novih, zaraznijih sojeva, zbog čega odvojeni izveštaj u medicinskom žurnalu piše o zabrinutosti zbog mutiranih tipova kovida.


    Fajzer i Moderna su saopštili da rade na ažuriranju njihovih vakcina ili mogućnosti davanja još jedne doze, ukoliko bude potrebna protiv novih sojeva.


    (b92)


    Ovo je baš kratko vreme delovanja. Pritom, moj nereprezentativni uzorak od četvoro prekookeanaca kaže da Moderna ima jake nuspojave, slične onima koje opisuju ljudi koji su primili AZ.


    Samo... jak im uzorak.
    Nije kratko vreme delovanja nego za sest meseci imaju podatke. Ne mogu da kazu traje najmanje 12 meseci kad su poceli da prate od pre sest meseci. Ovo ne znaci da imunitet nestaje nalon sest meseci vec da i nakon sest meseci jos uvek drzi.


    _____
    you cannot simply trust a language model when it tells you how it feels
    kondo

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    Post by kondo Wed Apr 07, 2021 11:19 am

    dokle ovi fajzer moderna lobisti


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    #FreeFacu

    Дакле, волео бих да се ЈСД Партизан угаси, али не и да сви (или било који) гробар умре.
    lalinea

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    Post by lalinea Wed Apr 07, 2021 11:34 am

    Dok sinofarm ne izbaci valjane podatke VAKCINA - Page 14 2849097393


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    you cannot simply trust a language model when it tells you how it feels
    rumbeando

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    Post by rumbeando Wed Apr 07, 2021 12:05 pm

    U Srbiji je do sada dato više od 2.650.000 vakcina, od čega je 1.120.000 građana primilo i drugu dozu.


    https://www.rts.rs/page/stories/sr/%D0%9A%D0%BE%D1%80%D0%BE%D0%BD%D0%B0%D0%B2%D0%B8%D1%80%D1%83%D1%81/story/3134/koronavirus-u-srbiji/4324075/koronavirus-srbija-stanje-.html


    Govoreći o vakcinaciji stranaca u Srbiji, Jovanović je rekao da je do sada vakcinisano njih 39.000.


    https://www.rts.rs/page/stories/sr/%D0%9A%D0%BE%D1%80%D0%BE%D0%BD%D0%B0%D0%B2%D0%B8%D1%80%D1%83%D1%81/story/3134/koronavirus-u-srbiji/4324206/vakcinacija-prijava-slobodni-punktovi-koronavirus-samouprave.html
    Dambo

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    Post by Dambo Wed Apr 07, 2021 1:57 pm

    Amerika ne planira federalno nametanje vidova kovid pasoša 

    Covid: US rules out federal vaccine passports - BBC News
    rumbeando

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    Post by rumbeando Wed Apr 07, 2021 2:14 pm



    Spot je radio Dragojević.



    rumbeando

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    Post by rumbeando Wed Apr 07, 2021 2:24 pm

    Šef indijske firme koja pravi najviše vakcina na svetu žali se da ne može da poveća proizvodnju jer ga je vlada nagazila da prodaje vakcine gotovo bez profita po 10x manjoj ceni nego za inostranstvo i najavljuje da će u svojim pogonima praviti i Sputnjik V, a u budućnosti i nazalnu vakcinu Kodageniks, čije testiranje uskoro počinje.

    "Very Stressed, To Put It Frankly": Adar Poonawalla On Vaccine Supply

    India has administered around 8.3 crore [83 million] vaccine doses since the drive began on January 16, the Health Ministry said at a briefing on Tuesday evening

    New Delhi: Existing production capacity to manufacture Covishield, one of the two Covid vaccines being administered in India is "very stressed, to put it frankly", Serum Institute of India (SII) CEO Adar Poonawalla told NDTV on Tuesday evening.
    Mr Poonawalla said the SII - which produces between 60 and 65 million doses per month presently, has so far given around 100 million doses to the centre and exported 60 million - but is "still short of being able to supply to every Indian" who needs the vaccine.
    "The globe needs this vaccine... we are prioritising the needs of India (but) we are still short of being able to supply to every Indian," Mr Poonawalla said.
    He said SII needed ₹ 3,000 crore [340 million euros] - a shortfall linked to the deal with the government to sell a doses at a heavy discount - in order to ramp up capacity needed to scale up production by June.
    "We're supplying in India at approximately ₹ 150-160 [1.7-1.8 euros]. The average price is around $20 (Rs 1,500) [17 euros]... (but) because of the Modi government's request, we are providing at subsidised rates... It is not that we're not making profits... but we are not making super profits, which is key to re-investing," he said.
    "This (the amount needed) would be roughly ₹ 3,000 crores [340 million euros]. The process takes 85 days, so it would be just under three months before we scale up operations," he said, adding that he had written to the centre on this subject, failing which SII would approach the banks for a loan.
    Mr Poonawalla said that even if SII could increase its capacity - to around 100 million doses per month - India needed other manufacturers to also scale up in order to meet requirements.
    He also said export bans - last month the centre said it was pausing major Covishield shipments - and the 'first claim' deal with India were difficult to explain abroad, where it is sold at a substantially higher cost per dose.
    Last week the centre said there was no outright ban on the export of vaccines.
    The SII chief also said he was working towards making Russia's Sputnik-V, which is expected to get permission for use in India any day. He also said that Codagenix would enter trials soon.
    "Codagenix is going to be a single-dose nasal vaccine that is a potential gamechanger... will take time to develop.. we have to make sure the delivery mechanism delivers just the right amount of vaccine around the mucosa to prevent the virus from entering the system," Mr Poonawalla explained.
    "We're hoping it becomes super convenient to administer and also cuts transmission when you do get infected... that's the advantage of the nasal vaccine," he said.
    The introduction of multiple vaccines in India will help speed up vaccination - a critical point given the renewed spread of the virus and calls to widen the vaccine net.
    India has administered around 8.3 crore [83 million] vaccine doses since the drive began on January 16.
    The centre has said the pace of the rollout is second only to the United States - 79.11 million been vaccinated in 79 days (as on April 4) compared to 165.05 million in 112 days by the US.
    However, the alarming rate at which new cases are being reported every day means the vaccination effort has to be significantly faster to stop the virus from spreading.
    The Chief Ministers of Delhi, Maharashtra and Punjab, as well as the Indian Medical Association, have all asked Prime Minister Narendra Modi to allow more people to be vaccinated.
    At present, only those over 45, and healthcare and frontline workers, are eligible to get the shot.
    The centre on Tuesday rejected calls to allow more people to get vaccinated, saying the focus had to be on vaccinating those who needed it and not on those who wanted the shot.
    "We have to focus on Covid-appropriate behaviour and containment. When the time comes to open it to all, then we will," Dr VK Paul, a member of government think tank NITI Aayog, said.



    https://www.ndtv.com/india-news/coronavirus-vaccination-rs-3-000-crores-needed-to-ramp-up-vaccine-production-adar-poonawalla-2407614

    crore = 10 million
    rumbeando

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    Post by rumbeando Wed Apr 07, 2021 2:39 pm

    Inače, već postoji nosni sprej na bazi azot-monoksida koji ubija virus, čak je i odobren u Izraelu i na Novom Zelandu.






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    avatar

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    Post by MNE Wed Apr 07, 2021 2:52 pm

    ja sam prskao onu jodiranu vodu fazon morsku, tripujem se da mi je pomoglo
    Anonymous
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    Post by Guest Wed Apr 07, 2021 2:55 pm

    ovak sprej je tableta za dan posle

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