Home
by rumbeando Thu Aug 05, 2021 5:15 pmStudy: post-vax delta breakthrough infections are infrequent and when they occur, they're typically shorter in duration (with less potential for spread) than in unvaccinated. "Vaccination is associated with faster decline in viral RNA load." https://t.co/B009fsCPJ6 h/t @EricTopol pic.twitter.com/FmNnIxf1oU
— Scott Gottlieb, MD (@ScottGottliebMD) July 31, 2021
Rezultati:
Of 218 individuals with B.1.617.2 infection, 84 had received a mRNA vaccine of which 71 were fully vaccinated, 130 were unvaccinated and 4 received a non-mRNA. Despite significantly older age in the vaccine breakthrough group, the odds of severe COVID-19 requiring oxygen supplementation was significantly lower following vaccination (adjusted odds ratio 0.07 95%CI: 0.015-0.335, p=0.001). PCR cycle threshold (Ct) values were similar between both vaccinated and unvaccinated groups at diagnosis, but viral loads decreased faster in vaccinated individuals. Early, robust boosting of anti-spike protein antibodies was observed in vaccinated patients, however, these titers were significantly lower against B.1.617.2 as compared with the wildtype vaccine strain.
Zaključak te singapurske studije:
The mRNA vaccines are highly effective at preventing symptomatic and severe COVID-19 associated with B.1.617.2 infection. Vaccination is associated with faster decline in viral RNA load and a robust serological response. Vaccination remains a key strategy for control of COVID-19 pandemic.
MNE
